为探究淋巴管内皮细胞(LEC)维持机械稳定性的机制,研究人员开展相关研究,发现其形状的动态调节对淋巴管功能至关重要。 研究人员运用了多种关键技术方法。在实验动物模型方面,使用了多种基因工程小鼠,如 VE-cadherin-GFP 小鼠、iMb2-Mosaic 小鼠等,以便观察细胞和组织的特征 ...
这项研究发现,淋巴管内皮细胞通过精巧的细胞形态和动态调控的细胞骨架,有效地应对了液体压力变化带来的挑战,维持了淋巴管的完整性和功能。这些发现不仅加深了我们对淋巴系统基本生物学原理的理解,也为开发治疗淋巴系统相关疾病的新策略提供了潜在的靶点。
Optimal growth conditions for HIMEC cultures were established, allowing up to nine passages (three months in vitro). The cells contained Weibel-Palade bodies, expressed von Willebrand factor, CD31, ...
The lobate shape of lymphatic endothelial cells puzzled researchers—now they’ve found it helps stabilize lymphatic ...
Department of Neurosurgery, Beijing Tiantan Hospital (H.X., R.H., S.Z., Y.S., Jie Wang, Q.H., Q.Y., J.T., Y.J., Y.C.), Capital Medical University, China. China ...
Does the 2012 Holden Calais V VE Series II V6 live up to the nameplate and the statement made by the most luxurious Commodore variant? With the new 2012 VE Series II model you’d expect some ...
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