With aging there are changes in the cardiovascular system, which result in alterations in cardiovascular physiology. The changes in cardiovascular physiology must be differentiated from the ...
HUVECs were treated with 0.2 μM doxorubicin (Dox) for 48 h to induce cellular senescence. Considering the importance of ECs in cardiovascular aging, we further investigated the transcriptomic ...
Key vascular features including a dense vasculature, a tightly controlled environment, and the regulation of cerebral blood flow (CBF) all take part in brain health throughout life. As such, healthy ...
Systemic inflammation, aging, and type 2 diabetes (T2D) lead to varying degrees of cardiovascular dysfunction and impaired aerobic exercise capacity. This study evaluates the impact of inflammation ...
Women who go through menopause later in life have healthier blood vessels for years to come than those who go through it earlier, according to new University of Colorado Boulder research.
The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs). Aging and disease are associated with dramatic changes in ECM composition ...