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靶向脉络丛 SPAK:多发性硬化症治疗的新希望
目前,预防免疫细胞浸润大脑的疾病修正疗法(Disease-modifying therapies,DMTs)虽对 MS 治疗有一定效果,但却存在不可预测的副作用,比如会引发进行性多灶性白质脑病、全身反应(发热、寒战)以及胃肠道紊乱(恶心)等。这使得开发更安全的治疗方法迫在眉睫。
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