The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring. [1] Friedel–Crafts reactions are of two main types: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitution. [2] [3] [4] [5]

A Friedel-Crafts reaction is an organic coupling reaction involving an electrophilic aromatic substitution that is used for the attachment of substituents to aromatic rings. The two primary types of Friedel-Crafts reactions are the alkylation and acylation reactions.

傅里德-克拉夫茨反应（英文：Friedel–Crafts reaction），简称傅-克反应，是一类芳香族亲电取代反应，1877年由法国化学家查尔斯·弗里德爾（Charles Friedel）和美国化学家詹姆斯·克拉夫茨（James Mason Crafts）共同发现 [1] 。

Friedel-Crafts反应 ，简称傅-克反应，是一类芳香族亲电取代反应，1877年由法国化学家Charles Friedel和美国化学家James Mason Crafts共同发现。该反应主要分为两类：烷基化反应和酰基化反应。

2024年5月6日 · In this article, we will read in detail about the Friedel Craft Reaction, its types, mechanisms, and examples. What is Friedel Craft's Reaction? When substituents are attached to aromatic rings, an organic coupling process called a Friedel-Crafts reaction takes place.

2020年6月21日 · The reaction of an aromatic substrate with an acid chloride (or acid anhydride) in the presence of an aluminum chloride catalyst is used to introduce an acyl group (C=O) into the aromatic ring through an electrophilic aromatic substitution mechanism. Such reactions are Friedel-Crafts acylation reactions.

2018年5月17日 · Friedel Crafts Alkylation and Acylation. Aromatic rings will form C-C bonds when treated with alkyl or acyl halides in the presence of a strong Lewis acid (e.g. AlCl 3). These are known as Friedel Crafts reactions and are examples …

Called the Friedel–Crafts reaction after its founders in 1877, Charles Friedel and James Crafts, the reaction is carried out by treating an aromatic compound with an alkyl chloride, RCl, in the presence of AlCl 3 to generate a carbocation electrophile, R +.

2023年10月6日 · Friedel-Crafts reactions generate new C-C bonds in organic molecules. The aromatic molecule is alkylated or acylated in the presence of an acid catalyst, such as AlCl 3, BF 3, ZnCl 2, FeCl 3, and so on. In Friedel-Crafts reactions catalyst’s role is to produce the attacking particle, an alkyl or an acyl cation.

In this lab, we successfully completed a Friedel-Crafts alkylation reaction with accept-able purity (as measured by TLC, melting-point, and NMR analysis) and comparatively excellent yield.