If you have treatment-resistant depression (TRD), know that you’re not alone. About 30% of people with major depressive disorder have it. There are several treatment options for TRD, but it’ll likely take time to find the best one for you.

Treatment resistant depression affects about 30% of people diagnosed with major depressive disorder. Here is what you should know about treatment resistant depression and the range of options for treatment.

2021年4月10日 · If you've been treated for depression but your symptoms haven't improved, you may have treatment-resistant depression. Taking an antidepressant or going to psychological counseling (psychotherapy) eases depression symptoms for most people.

2022年7月6日 · Treatment-resistant depression is generally defined as a type of depression that doesn’t respond to treatment after a certain amount of time. Specifically, this is when a person doesn’t have a significant improvement after two courses of different antidepressants.

Treatment-resistant depression (TRD) is major depressive disorder in which an affected person does not respond adequately to at least two different antidepressant medications at an adequate dose and for an adequate duration. [1] .

Our review of the evidence suggests that further large-scale work is necessary to understand the appropriate treatment pathways for TRD and to prescribe effective therapeutic options for patients suffering from TRD.

2024年9月5日 · Most people can get their treatment-resistant depression under control. You and your doctor just need to find the right approach. This might include different drugs, therapy, and other...

2024年7月16日 · Taking an antidepressant or going to psychological counseling (psychotherapy) eases depression symptoms for most people. But with treatment-resistant depression, standard treatments aren’t enough. They may not help much at all, or your symptoms may improve, only to keep coming back.

2024年11月14日 · Standard treatments ease depression for a lot of people, but they don't work for everyone. At least 30% of those who try two or more antidepressants continue to have serious symptoms. That's...

Two medications approved by the Food and Drug Administration (FDA) for treatment-resistant depression are olanzapine/fluoxetine (Symbyax®) and intranasal esketamine (Spravato ®). 4 Another option for treatment-resistant depression is ketamine.