A: Blue arrows - Circinate exudates, defined as exudates arranged in a circular appearance. B: OCT b-scan across the fovea confirming the presence of DME associated with an elevated foveal contour. The patient’s best-corrected vision was 20/32. Risk factors for DME and DR are similar.

2021年5月1日 · DME, which is characterized by hard exudates and edema within the macula secondary to damage to retinal microvasculature, is detected by clinical examination or with OCT. Before the advent of pharmacotherapy for DME, the first-line treatment was tradition­ally focal laser photocoagulation of the macula.

Diabetic macular oedema (DMO) is a thickening of the central retina, or the macula, and is associated with long‐term visual loss in people with diabetic retinopathy (DR). Clinically significant macular oedema (CSMO) is the most severe form of DMO.

2014年5月14日 · 2.1. OCT in Diabetic Macular Edema. DME is the most common cause of moderate visual loss in patients with diabetes [].In 1998, Hee et al. were the first to use OCT to measure the retinal thickness in patients with DME [].As a result, OCT imaging has rapidly been integrated into diagnosis and management of DME in routine clinical practice and clinical trials [].

Purpose: : To describe various morphologic patterns of diabetic macular edema demonstrated by optical coherence tomography (OCT) and propose a new classification of this clinical entity based on OCT findings. Methods: : We carried out a prospective study including 314 eyes of 174 patients with diabetic retinopathy at different stages.

2013年7月24日 · Diabetic retinopathy is estimated to affect one-third of patients with diabetes. The prevalence and severity are affected by the duration of diabetes, glycemic control, and the presence of concurrent hypertension. Epidemiologic studies suggest that diabetic macular edema (DME) will affect up to 7 % of patients with diabetes [1].

Purpose: More than ten years after ETDRS, Optical Coherence Tomography (OCT) greatly enhanced our ability to detect macular thickening and has brought new insights on the morphology of edema and on the presence of vitreal traction. In this study we propose a new classification of macular edema based on OCT findings to better catalogue and ...

2023年2月13日 · Diabetic macular edema (DME) and proliferative diabetic retinopathy are the most common causes of vision loss in diabetic retinopathy. A simplified understanding of the pathogenesis of DME formation is depicted in Figure 1: The role of vascular endothelial growth factor (VEGF) and inflammation in the pathogenesis of DME is depicted in Figure 2:

2024年3月19日 · There is a variable response to anti-VEGF agents in patients with diabetic macular edema (DME), with some patients needing frequent injections and experiencing irreversible vision loss even after achieving anatomic success.

Keywords: Aflibercept; Anti-VEGF; Diabetic macular edema; Diabetic retinopathy; OCT. MeSH terms Angiogenesis Inhibitors / administration & dosage